To alleviate suffering & improve the quality of life of patients with incurable or intractable disorders & injury of the nervous system, by restoring functional abilities to a maximum possible, by extending a professional, holistic & caring manner, and to conduct basic & clinical research by constant work on innovation & development, so that the best therapeutic strategies can be evolved.
Some time ago donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: They can grow into specialized cell types such as nerve cells, muscle cells, and blood cells.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. See extra details on NeuroGen Hospital.
Knowing the Specialists: Managing all aspects of a child’s unique diagnosis is essential for successful comprehensive treatment. Well-rounded treatment approaches require a team of multidisciplinary specialists, usually with a pediatrician at the center of the group. Pediatricians are generalists who manage the treatment plan, recognize specific issues and recommend specialists who can treat those issues. Each specialist uses ongoing treatment and assessments to ensure that all areas of the child’s development are proceeding as normally as possible. Scoliosis (spinal curvature) and shortened achilles tendons are some specific movement and posture issues that are treated with physical therapy. Physical therapy is an important prevention measure, as these issues can get worse over time. Proper treatment of the above conditions can also improve the chance of a child walking independently.
A few advices to help your child with autism: There are many things parents can do to help children with Autism Spectrum Disorder (ASD) overcome their challenges. But it’s also important to make sure you get the support you need. When you’re looking after a child with ASD, taking care of yourself is not a luxury or an act of selfishness-it’s a necessity. Being emotionally strong allows you to be the best parent you can be to your child in need. These parenting tips can help by making life with an autistic child easier. While it is true that ASD is not something a person simply “grows out of,” there are many treatments that can help children acquire new skills and overcome a wide variety of developmental challenges. From free government services to in-home behavioral therapy and school-based programs, assistance is available to meet your child’s special needs. With the right treatment plan, and a lot of love and support, your child can learn, grow, and thrive.
What’s the long-term outlook? Some people lead full and productive lives after a spinal cord injury. However, there are severe potential effects of a spinal cord injury. The vast majority of people will need assistive devices such as walkers or wheelchairs to deal with loss of mobility, and some may even be paralyzed from the neck down. You may need assistance with daily living activities and learn to perform tasks differently. Pressure sores and urinary tract infections are common complications. You also may expect to undergo intense rehabilitation treatment for your spinal cord injury.
Did you know that stem cells, unlike other cells in the body, continue to divide for long periods of time and can help strengthen the immune system, effectively fighting infections and pathogens from the external environment. In addition, stem cells in the placenta and umbilical cord are important sources of platelets and red cells, which carry oxygen and nutrients to the blood. Stem cell harvesting can be done regardless of the time of birth: vaginal birth, caesarean section, multiple birth, premature birth or water birth.
Muscular Dystrophy encompasses a group of genetic disorders which are characterised by progressive loss of muscle mass and subsequent weakness. Dystrophy is coined from the Greek word which essentially means ‘bad nourishment’. Early detection of muscular dystrophy started with a study by Sir Charles Bell, on the increasing weakness of the muscles of young boys, in 1830. This study on Muscular Dystrophy talks about a set of less than 30 genetic diseases that can lead to an alarming rate of increasing weakness of skeletal muscles applied through all voluntary movements. All these different ailments differ through the arrival stage, seriousness and prototype of muscles that are affected. All the manifestations of muscular dystrophy worsens as the muscles continually deteriorates and starts to weaken, and hence, it is considered as a “progressive muscular disorder”. See extra details Muscular Dystrophy Stem Cell Treatment.